What types of preservative fluids are there for virus sampling tubes?

The preservation fluid of virus sampling tubes mainly has the following two types:

I. Inactivated preservation fluid

1. Characteristics:
   • It can quickly inactivate the virus, making the virus lose its infectivity, thereby reducing the biosafety risk during sample transportation and processing.
   • It can effectively prevent the virus from continuing to proliferate after sampling and ensure the stability of the viral nucleic acid in the sample.
2. Components:
   • Usually contains compounds such as guanidine salts, such as isothiocyanic acid guanidine or guanidine hydrochloride. These substances can destroy the protein shell of the virus and make the virus inactive.
   • It may also contain other components such as buffers and preservatives to maintain the stability of the pH value of the preservation fluid and prevent bacterial contamination.

II. Non-inactivated preservation fluid

1. Characteristics:
   • It can maintain the activity of the virus and is suitable for culturing the virus and further research.
   • It can retain the original characteristics of the virus to the greatest extent and provide more accurate samples for the isolation, identification and analysis of the virus.
2. Components:
   • Generally contains nutrients and buffer systems required for the survival of the virus, such as normal saline, phosphate buffer solution, etc.
   • Some protectants such as bovine serum albumin and antibiotics may be added to prevent the virus from being damaged and contaminated during preservation.
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